The most common tumor of the urinary tract is transitional cell carcinoma. It is associated with Phenacetin, smoking, aniline dyes and cyclophosphamide.
Squamous cell carcinoma is due to chronic irritation of the bladder as seen with S.Hematobium infection, chronic cystitis and smoking.
Renal cell carcinoma is the most common primary renal malignancy. Gene deletion on chromosome 3. Often golden yellow due to high lipid content. Can present with hematuria, palpable flank mass, secondary polycythemia. Associated with paraneoplastic syndromes.
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